Cost-Effectiveness of Ofatumumab Plus Chlorambucil in First Line Chronic Lymphocytic Leukemia in Canada.

Table 1. Drug Acquisition, Administration, and Monitoring Costs for FirstLine Treatment With OChl and Chl Cost Type OChl Chl Drug acquisition Ofatumumab, 100 mg vial $336 – Chlorambucil, 25 x 2 mg pack $35 $35 Administration Induction infusion in first cycle (O) $1,039 – Regular infusion in subsequent cycles (O) $818 – Oral chemotherapy dispensing (Chl)a $9 $9 Monitoring (per chemo cycle)b $119 $119 Premedications (per chemo cycle) $10 – aThe dispensing fee is per 6 months of drug. bCosts include hematologist visit, complete blood count, and biochemistry.